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Melanocortin receptor agonists. Melanocortin receptor agonists including melanotan II (subcutaneous administration) and bremelanotide (intranasal administration) have been studied for ED. Both formulations improved erectile function in studied men, although they were poorly tolerated in clinical studies. Patients given melanotan II experienced severe emesis, and bremelanotide caused severe hypertension. Further clinical development has been discontinued. "In terms of sexual health, erectile dysfunction (ED) is the most common problem men report to their doctor," says Dr. Nathan Starke, urologist specializing in men's health at Houston Methodist. "Most often, men are prescribed an oral medication such as 'the blue pill' or one of its closely related alternatives." Dr. Femi Aremu is a clinical pharmacist with experience in medication therapy management, custom compounded medications, medicinal cannabis, and is interested in health technology. Additionally, Dr. Aremu is a cannabis advocate with experience in cannabis extraction. article source.

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Further clinical development has been discontinued. “To think the teachers are very busy, they have a lot on their plates, but they actually took the time to practise… It really left a mark.